Fig. 6: A7 DLBCL tumors have low levels of immune infiltration and reduced MHC expression. | Nature Communications

Fig. 6: A7 DLBCL tumors have low levels of immune infiltration and reduced MHC expression.

From: Transcriptomic classification of diffuse large B-cell lymphoma identifies a high-risk activated B-cell-like subpopulation with targetable MYC dysregulation

Fig. 6: A7 DLBCL tumors have low levels of immune infiltration and reduced MHC expression.

A Deconvolution plot of inferred immune cell populations as enriched or depleted in A7 relative to non-A7 patients. B Scatter plot of the Discovery cohort in the space of Reddy COO score vs. TME26 score. C Single channel MIBI images for indicated markers in representative A7 (red) and non-A7 DLBCL cases (gray). D Multiplexed MIBI images for indicated markers in representative A7 (red) and non-A7 DLBCL cases (gray). Source data are provided as a Source Data file.

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