Fig. 4: Phenotype Consequences.
A LabWAS of PGSTCF in individuals of European Ancestry. The direction of the triangle indicates the PGS is associated with increased (Δ) or decreased (∇) levels of the lab value (Prediction N = 57,392, Target N = 72,828). The test performed was two-sided, the solid red line represents our Bonferroni multiple-hypothesis correction p-value threshold for significance, and the blue line indicates a p-value of 0.05. B T-cell fraction decreases throughout the first and second trimesters (weeks 1–13 and 14–26) and increases in the final trimester (27–40 weeks). Data are presented as mean values +/− SEM (N = 659, Age-matched control N = 659).
