Fig. 3: Seizures induce stereotypy among spiking bursts.
From: Focal seizures induce spatiotemporally organized spiking activity in the human cortex
a Spearman’s rank correlation (Fisher z-transformed ρ) between spiking sequences of every seizure burst in this same example seizure. To extract a time-evolving measure of spike sequence consistency, we computed the correlation between each spiking burst and its eight nearest temporal neighbors (8nn; see inset). b Timecourse of similarity of each seizure burst to eight nearest temporal neighbors in this example seizure (three-second moving average in black). The example seizure bursts from Fig. 1 are highlighted with gray rings. c There is a strong correlation between distance from baseline centroid (Fig. 2c) and time-evolving self-similarity of seizure bursts for this example seizure (ρ = 0.70). d Average correlations between distance from baseline centroid and time-evolving self-similarity for seizure bursts across all seizures in all participants, for n = 6 arrays. For each array in each participant, the weighted average of the correlation is shown (dark blue) along with the 95% confidence interval (light blue). The average correlation across all participants and arrays is shown below (dark blue vertical line and error bar). × indicates participant 1.
