Fig. 5: Simulated mitotic chromosome. | Nature Communications

Fig. 5: Simulated mitotic chromosome.

From: Single-nucleosome imaging unveils that condensins and nucleosome–nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes

Fig. 5

a, b Coarse-grained Brownian dynamics modeling of mitotic chromosome based on previous work91 and models (Supplementary Fig. 4d)25,26. Chromatin beads, condensin I, and condensin II are represented by blue, red, and green spheres, respectively. Also see Supplementary movie 5. Simulated mitotic chromosome without condensin I (c) or condensin II (d), respectively. Also see Supplementary movies 6 and 7. e Calculated MSDs (±SE among 10 chromosomes) of randomly identified points on the chromatin fibers of simulated chromosomes under the indicated conditions. Simulated mitotic chromosome without condensins (f) and that in a cylinder with restraint, where global constraining was provided (g). Also, see Supplementary movies 8 and 9.

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