Fig. 2: Scope of the Fe-catalyzed hydrohalogenation and hydrofunctionalization of mono-, di- und trisubstituted alkenes including natural products.
From: Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes
X-ray structure of the HCl salts derived from 8n and 8p, as well as of azide 8q. Reactions were carried out on a 0.2–0.5 mmol scale and all yields provided refer to isolated yields. Diastereoselectivity (if applicable) was determined by GC or NMR analysis, and the relative configuration was assigned by X-ray analysis of single crystals or in analogy to a known related compound, see Supplementary Material.aNMR yield. bSee Supplementary Material for the procedure.
