Table 2 Treatment-related and procedural-related adverse events

From: Cryoablation and post-progression immune checkpoint inhibition in metastatic melanoma: a phase II trial

Treatment-related adverse events

Procedural adverse events

Type

Any grade

Grade 3–4

Type

Any grade

Grade 3–4

Rash

2

0

Pain

9

1

Fatigue

3

0

Pneumothorax

2

0

Arthralgias

2

0

Wound Complicationa

2

1

Anorexia

1

0

Procedural Complicationb

1

0

Diarrhea

1

0

Cough

1

0

Adrenal Insufficiencyc

1

1

Transient lab abnormalityd

2

2

  1. aDevelopment of osteomyelitis after cryoablation of clavicular lesion (grade 3)
  2. bDiaphragmatic puncture (grade 2)
  3. cFlare of pre-existing adrenal insufficiency s/p cryoablation (grade 4)
  4. dTransient LFT elevation in one patient s/p cryoablation of a liver lesion, transient creatinine elevation in one patient s/p cryoablation of a renal lesion
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