Fig. 5: Protein mutation profiles across clade IIb MPXV.

A Heatmap showed the average mutation numbers across each lineage, and clusters of 175 proteins in MPXV genome across 27 lineages. Proteins were annotated and colored by 5 functional classes. The proteins specifically contained in each cluster can be found in Supplementary Data 2. B Stacked bar chart displayed the total mutation number of each OPG across 5220 MPXV genomes by 5 mutation types. C Bar chart presented normalized mutation number by gene length of each OPG.