Fig. 2: Morphometric correlates of the sensory-association (S-A) axis of functional cortical organization across sexes. | Nature Communications

Fig. 2: Morphometric correlates of the sensory-association (S-A) axis of functional cortical organization across sexes.

From: Sex differences in functional cortical organization reflect differences in network topology rather than cortical morphometry

Fig. 2

A Mean S-A axis loadings (spanning from visual to default-mode regions) across sexes; B Mean microstructural profile covariance (MPC) axis loadings (spanning from sensory to paralimbic regions) across sexes; C Mean geodesic distance of connectivity profiles across sexes; D Thresholded β-map of linear mixed effect model (LMM) results showing false discovery rate (FDR)-corrected statistically significant effects (q < 0.05) of total surface area on the S-A axis loadings; E Thresholded β-map of LMM results showing FDR-corrected statistically significant effects of MPC axis loadings on the S-A axis loadings; F Thresholded β-map of LMM results showing FDR-corrected statistically significant effects of mean geodesic distance on the S-A axis loadings; G Spatial correlation between mean patterns of S-A axis loadings and mean patterns of MPC axis loadings (color-coded by functional Yeo network), tested by a two-sided Spearman correlation and corrected for spatial autocorrelation, r = 0.20, pspin = 0.037. Error band displays 95% confidence interval; H Spatial correlation between mean patterns of S-A axis loadings and mean patterns of mean geodesic distance (color-coded by Yeo network), tested by a two-sided Spearman correlation and corrected for spatial autocorrelation, r = 0.76, pspin < 0.001. Error band displays 95% confidence interval. β standardized beta coefficient. Source data are provided as a Source Data file.

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