Fig. 5: Protein expression analysis in mouse brain tissue. | Nature Communications

Fig. 5: Protein expression analysis in mouse brain tissue.

From: Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier

Fig. 5: Protein expression analysis in mouse brain tissue.

A Representative fluorescent microscopy data of ICAM-1 expression at 8 h after MB-FUS treated with 150 kPa. Red, ICAM-1; green, CD31. B Quantification of ICAM-1 expression treated with 150 kPa (upper) and 175 kPa (lower) pressure (n = 4 for 150kPa group, n = 6 for 175 kPa group) (p = 0.011 for 150 kPa group, p = 0.006 for 175 kPa group). C Representative fluorescent microscopy data of IBA-1 expression at 8 h after MB-FUS treated with 150 kPa. Green, IBA-1; blue, DAPI. D Quantification of IBA-1 expression treated with 150 kPa pressure (n = 4, p = 0.049). Measurements were taken from distinct samples. Plots show means ± SD. P-values were determined by two-tailed paired t tests. *P ≤ 0.05, **P ≤ 0.01.

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