Table 2 Associations between persistence of clusters and individual demographic factors, size of cluster, and phenotypic antimicrobial resistance
From: Longitudinal genomic analysis of Neisseria gonorrhoeae transmission dynamics in Australia
Characteristic | Adjusted Odds ratio | 95% Confidence Interval | P-value | n/N | % |
|---|---|---|---|---|---|
Sex | |||||
Male | Reference | - | - | 1760/2805 | 62.7 |
Female | 2.910 | 1.21–7.00 | 0.017 | 284/367 | 77.4 |
Other | 0.749 | 0.189–2.97 | 0.681 | 17/30 | 56.7 |
Unknown | 0.111 | 0.00289–4.290 | 0.239 | 1/6 | 16.7 |
Age | |||||
16–19 years | Reference | - | - | 69/100 | 69.0 |
20–29 years | 0.682 | 0.316–1.470 | 0.328 | 816/1270 | 64.3 |
30–39 years | 0.616 | 0.318–1.190 | 0.151 | 695/1087 | 63.9 |
40–49 years | 0.483 | 0.197–1.190 | 0.113 | 319/493 | 64.7 |
50 years and older | 0.458 | 0.171–1.230 | 0.121 | 163/258 | 63.2 |
Size | |||||
Size | 1.020 | 1.000–1.030 | 0.030* | - | - |
Phenotype | |||||
Penicillin | |||||
Susceptible/less susceptible | 2.71 | 0.249–29.500 | 0.413 | 1743/2371 | 73.5 |
Resistant | Reference | - | - | 319/837 | 38.1 |
Tetracycline | |||||
Susceptible/intermediate | 1.800 | 0.292–11.100 | 0.525 | 1190/1411 | 84.3 |
Resistant | Reference | - | - | 872/1797 | 48.5 |
Ciprofloxacin | |||||
Susceptible/less susceptible | 2.620 | 0.320–21.200 | 0.368 | 1838/2409 | 76.3 |
Resistant | Reference | - | - | 224/799 | 28.0 |
Ceftriaxone | |||||
Susceptible | 0.130 | 0.016–1.060 | 0.057 | 2050/3195 | 64.2 |
Decreased susceptibility | Reference | - | - | 12/13 | 92.3 |
Azithromycin | |||||
Susceptible | 126 | 12.900–1238 | 0.0000326 * | 2052/2991 | 68.6 |
Resistant | Reference | - | - | 10/217 | 4.6 |
