Fig. 4: Verification of BioES-suture in accelerating wound healing in vivo.
From: A bioabsorbable mechanoelectric fiber as electrical stimulation suture
a Schematic showing how BioES-suture promoted muscle wound healing. b Comparison of electromyography (EMG) signals in three groups. Including the unsutured (control) group, the bioabsorbable suture (Bio-suture) group and the BioES-suture group. c Representative optical images of wound areas after 10 days of recovery in each group. Scale bar: 500 μm. d H&E and Masson staining images of tissue sections the wounds and adjacent muscle areas. Scale bar: 100 μm. e Immunohistochemistry staining images of multiple growth factors including EGF, TGF-β, and VEGF-A. Scale bar: 100 μm. f Analysis of the wound closure rate after 10 days of recovery in each group. n = 4 independent samples. The box represents the 25–75% confidence interval, the triangle represents the mean, the error bars represent the standard deviation, and the horizontal line in the box represents the median. g Immunofluorescence score of the various growth factors expressed in each group. n = 4 independent samples. All statistical analyzes were performed by one-way ANOVA, data represent mean ± standard deviation, **p < 0.01, ***p < 0.001.
