Table 1 The allosteric site residues predicted the two representative conformations (Conf1 and Conf2) of the cluster1 category

Conf1

TM2\TM3\TM5

\TM6\TM7

L75^2.46, A76^2.47, A78^2.49, D79^2.50, M82^2.53, D113^3.32, C116^3.35, V117^3.36, S120^3.39, I121^3.40, L124^3.43, F208^5.47, F282^6.44, W286^6.48, L311^7.38, N312^7.39, I314^7.41, G315^7.42, Y316^7.43, N318^7.45, S319^7.46, N322^7.49, Y326^7.53

Conf2

TM2\TM3\TM5

\TM6\TM7

L75^2.46, A78^2.49, D79^2.50, M82^2.53, C116^3.35, V117^3.36, S120^3.39, I121^3.40, L124^3.43, F208^5.47, F282^6.44, W286^6.48, G315^7.42, Y316^7.43, N318^7.45, S319^7.46, N322^7.49