Fig. 3: Sequences of three types of nonfunctional resistance alleles. | Nature Communications

Fig. 3: Sequences of three types of nonfunctional resistance alleles.

From: Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila

Fig. 3: Sequences of three types of nonfunctional resistance alleles.The alternative text for this image may have been generated using AI.

Each sequence originates from one female carrying a resistance allele with the listed phenotype. Vertical dashed lines indicate the boundaries of the female-specific exon’s coding sequence. Orange highlighting shows the gRNA target sequences, and yellow shows the gRNA PAM sequences.—indicates deletion. “Insertion” refers to a 311 bp region from the right side of the drive that was copied by incomplete homology-directed repair.

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