Fig. 6: Comparison of the performance of SIT, fsRIDL, and RIDD system. | Nature Communications

Fig. 6: Comparison of the performance of SIT, fsRIDL, and RIDD system.

From: Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila

Fig. 6: Comparison of the performance of SIT, fsRIDL, and RIDD system.The alternative text for this image may have been generated using AI.

A constant number of drive heterozygous males/transgenic males were released each generation at with the number based on the specified ratio of released males to males in the starting population (that is release ratio). The heatmaps show the outcome of stochastic simulations for suppression of a population of 100,000 with overlapping generations and a linear density growth curve. a The blue heat bar shows the average number of weeks to population elimination. b The red heat bar represents the average number of fertile females at equilibrium when population elimination was not successful before 267 weeks. The released RIDD-split drive males are homozygous for the Cas9 allele. Each point in the parameter space had 20 replicates. Note the different vertical axis scale for SIT and fsRIDL. Gray means “not applicable” (NA - where population elimination always occurred for (a), and where it never occurred for (b).

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