Fig. 6: Microbiota wellbeing index (MWI).

a Wellbeing index and microbial associations, measured as estimates from a logistic regression model predicting membership to the reference group. Top bar colours represent the bacterial class. b Wellbeing index values over time for Reference (green;) defined as children with no diagnosed allergic diseases or growth below or above the 2 sd during the first 5 years of life in T1, Growth differences (orange) defined as those children with weight below/above the 2 sd and height <2 sd during the first 5 years of life, and Allergic diseases (purple) defined as those children with allergy, atopy, rhinitis or asthma during the first 5 years of life, showing the means (lines) and the percentage (0.5,0.8,0.95) of the population within the scale. c Area under the curve (AUC) values from logistic regression models predicting health outcomes with MWI measured at different ages: ***p < 0.001, **p < 0.01, *p < 0.05, · p < 0.1. Only prospective associations are included. d Associations between MWI and infant exposures. No adjustments were made for multiple comparisions.