Fig. 6: Continued FASII activity in the mFabT mutant leads to lower eFA incorporation. | Nature Communications

Fig. 6: Continued FASII activity in the mFabT mutant leads to lower eFA incorporation.

From: The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection

Fig. 6: Continued FASII activity in the mFabT mutant leads to lower eFA incorporation.The alternative text for this image may have been generated using AI.

Membrane FA profiles were compared in WT and mFabT strains grown in THY-C17:1 (100 µM), containing or not the FASII-inhibitor platensimycin (1 µg/mL−1). Left, Representative FA profiles; right, quantified proportions of major FAs. Both strains grew in C17:1 regardless of the presence of platensimycin (Supplementary Table 6). N = 3, where N corresponds to the number of independent biological replicates used in analyses. Data are presented as mean values +/- SEM; 2-way ANOVA, Bonferroni post-test was performed. Significant p-values are shown. WT (black lines, white bars) and mFabT (green lines and bars). Source data are provided as a Source Data file.

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