Fig. 5: Tissue-specific expression of FOLR-1 to rescue folr-1 mutants for egg laying in response to 10F-THF. | Nature Communications

Fig. 5: Tissue-specific expression of FOLR-1 to rescue folr-1 mutants for egg laying in response to 10F-THF.

From: A specific folate activates serotonergic neurons to control C. elegans behavior

Fig. 5

a The number of eggs laid by wild type, tph-1(mg280) and egl-1(n487) mutants with 10F-THF or control buffer, added at the same concentration as for the experiments in Fig. 2 (n = 10). b The number of eggs laid by folr-1(ek44) mutant strains with FOLR-1 expressed in the indicated tissues in response to 10F-THF or control buffer (n = 20 except for NSM + vpi + isPharynx, which is n = 30). Data are presented as mean ± SEM. A paired two-tailed Student’s t-test was conducted for statistical analyses, n = groups of ten animals. Source data are provided as a Source Data file. ns not significant, vpi pharyngeal-intestinal valve cells, isPharynx the isthmus of the pharynx.

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