Table. 1 Patient characteristics. Source data are provided as a Source Data file

From: Tumour-informed liquid biopsies to monitor advanced melanoma patients under immune checkpoint inhibition

Patient characteristics

No° patients

%

Total

 

87

100

Sex

Female

38

44

 

Male

49

56

Age at start of immune checkpoint inhibitor [median; IQR]

64; 56–76 years

Melanoma type

  
 

Cutaneous

67

77

 

Occult

6

7

 

Uveal

1

1

 

Acral

7

8

 

Mucosal

6

7

Adjuvant cohort (Nivolumab/Pembrolizumab)

22

 
 

Stage I + II/III/IV at initial diagnosis

10/12/0

 
 

Tumour-free stage III at treatment start

22

 
 

Patient alive at last follow-up

19

 

Palliative cohort (Ipilimumab + Nivolumab)

65

 
 

Stage I + II/III/IV at initial diagnosis

28/22/15

 
 

Unresectable stage IV at start of combined ICI

65

 
 

First line treatment

28

 
 

LDH elevated* at start of combined ICI

34

 
 

S100 elevated** at start of combined ICI

38

 
 

Patient alive at last follow-up

29

 
  1. * >250 U/l, ** ≥0.1 µg/l.