Fig. 4: The structure and working principle of S-RIAMs and R-RIAMs. | Nature Communications

Fig. 4: The structure and working principle of S-RIAMs and R-RIAMs.

From: Multi-scenario surveillance of respiratory viruses in aerosols with sub-single-copy spatial resolution

Fig. 4: The structure and working principle of S-RIAMs and R-RIAMs.

a Structural overview of S-RIAMs and exploded schematic of its functional parts, including a cyclone bioaerosol sampler unit (i), a microfluidic cartridge sampling unit (ii), microfluidic cartridges loading tray (iii), and a control and detection system for performing fluid actuation, PCR temperature control, and fluorescence signal read-out (iv). b Optical image of S-RIAMs showing its 3D dimensions. c Optical image of R-RIAMs showing its 3D dimensions. d Schematic illustration of the microfluidic cartridge sampling process. e Ct values of viral RNA samples before and after transfer through the sampling system, verifying that there is no adsorption of viral RNA within the sampling systems inside the S-RIAMs and R-SIAMs. Error bars represent mean ± SD (n = 3 independently transferred or not-transferred samples).

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