Fig. 3: Multi-ancestry meta-analysis of glycated Haemoglobin (HbA1c).
From: Genetic architecture of routinely acquired blood tests in a British South Asian cohort
Manhattan plots showing the GWAS of HbA1c in the multi-ancestry meta-analysis (top panel), the Genes & Health GWAS (second panel), the UKB EUR GWAS (third panel), and the P values for ancestral heterogeneity (bottom panel) for each SNP derived from the meta-analysis. Selected genes are highlighted. Multi-ancestry meta-analysis was conducted using MR-MEGA. Ancestral heterogeneity P values refer to the strength of evidence supporting the hypothesis that SNP effect sizes at a locus were correlated with ancestral principal components, derived from summary statistics.
