Fig. 1: The principle of photoacoustic (PA) detection of circulating infected cells in vivo with an acoustic resolution Cytophone.
From: Noninvasive in vivo photoacoustic detection of malaria with Cytophone in Cameroon

a Schematic of the focused ultrasound transducer array for assessing a blood network. b Typical PA signal waveform from iRBCs in superficial and deep vessels (top), and PA trace from single and aggregated iRBCs at low and high concentrations in the blood background and motion artifacts (bottom). c Schematic of Cytophone with the optical, multichannel acoustic, and electronic recording system. PA photoacoustic, iRBC malaria-infected red blood cell, μs microsecond, s second, nm nanometer.