Table 1 Overview of existing and newly-added stratification types for the three reference genomes
From: The GIAB genomic stratifications resource for human reference genomes
Stratifications | GRCh37 | GRCh38 | CHM13 | |
Established set | Gene coding regions | ✓ | ✓ | This study |
Functional, technically difficult to sequence | ✓ | ✓ | NA | |
GC content | ✓ | ✓ | This study | |
Genome specific | ✓ | ✓ | NA | |
Regions with low complexity sequences | ✓ | ✓ | This study | |
Other difficult genomic regions | ✓ | ✓ | This study | |
Segmental duplications | ✓ | ✓ | This study | |
Chromosome XY specific regions | ✓ | ✓ | This study | |
Patterns of local ancestry | X | ✓ | NA | |
Low mappability regions | ✓ | ✓ | This study | |
Exploratory set for future versions | Variant complexity in tandem repeats | This study | ||
Distribution of genomic distance between consecutive variants | This study | |||
Read coverage of each variant | This study |
