Fig. 8: TMT analysis uncovers the causes of crush injury to MPG between the injury and sham groups. | Nature Communications

Fig. 8: TMT analysis uncovers the causes of crush injury to MPG between the injury and sham groups.

From: A tissue bandage for pelvic ganglia injury

Fig. 8: TMT analysis uncovers the causes of crush injury to MPG between the injury and sham groups.The alternative text for this image may have been generated using AI.

a Volcano plots of differential expression proteins (DEPs) between two groups. b–d GO, KEGG enrichment, and PPI network of DEPs between two groups. Neuro related proteins circled by red dot line, immunity circled by blue dot line, lipometabolism circled by green dot line, and others by yellow dot line. e The related heatmaps are based on the Protein-PPI topology network. Red dots indicate up-regulated proteins, yellow dots indicate no significant change proteins, and blue dots indicate down-regulated proteins. The dotted line color corresponds with the PPI categories. n = 3. A two-tailed t-test was conducted on the relative quantitative values of each protein in two comparison samples, followed by multiple comparisons with Bonferroni correction. Upregulated proteins: FC ≥ 1.5 and p value ≤ 0.05. Downregulated proteins: FC ≤ 0.67 and p value ≤ 0.05. Source data are provided in NC._data_file_s1.

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