Fig. 3: XCI ratios are not associated with X-linked heterozygosity.
From: Population variability in X-chromosome inactivation across 10 mammalian species
A Distributions of sample X-linked heterozygosity per species ordered by the median value. The y-axis is in log-10 scale, depicting the ratio of SNPs per sample to all unique identified SNPs per species. Box plots indicate median (middle line), 25th, 75th percentile (box) and 1.5 times the inter-quartile range from the first and third quartiles (whiskers) with sample numbers per species as follows: macaca n = 130, horse n = 275, dog n = 291, rat n = 369, mouse n = 388, goat n = 399, pig n = 654, sheep n = 784, cow n = 1364, human n = 4877. B The spearman correlation coefficients between sample X-linked heterozygosity and either the estimated standard deviation (SD) in X-linked allelic expression or the estimated XCI ratio of the sample (the SD and mean of the maximum-likelihood folded-normal model per sample). C 2D Scatter plots of sample heterozygosity compared to the sample estimated X-linked allelic expression SD for the three species with moderate correlation coefficients. Color bars represent the number of samples in each 2D bin. Plots for the other species are in Supplementary Fig. 7. Details for source data are provided in the Data and Code Availability statements.
