Fig. 2: Claustrum single units and slow-wave activity tracking over hours of sleep.

a Sleep recording from Subject B, Night 03. Hypnogram is colored by behavioral state observed on avEEG: red indicates wakefulness and blue indicates behavioral quiescence (first row). Power spectrogram from the C4 scalp electrode (second row). Illustrative power spectrogram from right middle frontal gyrus (third row). Binned z-score of slow-wave activity from four illustrative regions: middle frontal gyrus, amygdala, middle temporal gyrus, and orbitofrontal cortex (fourth row). Binned z-score of the firing rate for claustrum (blue), anterior cingulate cortex (green), and amygdala (orange) single units (fifth row). First principal component of the firing rate for single units in the above regions (sixth row). b Transition out of NREM sleep in Subject A. Power spectrogram of the left middle frontal electrode (first row). z-scored population firing rates in the claustrum (blue) and amygdala (orange) with black triangles indicating the transition period (second row). Magnified windows before and after sleep transition (bottom left and bottom right panels) showing SWA in the prefrontal cortex, insula, temporal lobe, and parietal lobe (first rows of bottom panels) and raster plots of spiking activity for the claustrum (second rows of bottom panels) and amygdala (third rows of bottom panels).