Fig. 1: Axially Chiral Allenes Containing Organoboron. | Nature Communications

Fig. 1: Axially Chiral Allenes Containing Organoboron.

From: Axially chiral α-boryl-homoallenyl boronic esters as versatile toolbox for accessing centrally and axially chiral molecules

Fig. 1

a Synthesis of axially chiral allenes bearing organoboron group. b Previously known gem-diboron compounds and remaining challenge. c Synthesis and diversifications of axially chiral α-boryl-homoallenyl boronic esters (this work). d Evaluation of reaction conditions (See the Supplementary information for details). Bpin: (pinacolato)boryl; Me: methyl; Ph: phenyl; Ac: acetyl; THF: tetrahydrofuran; Ar: aryl group; PG: protecting group.

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