Fig. 1: Spatial single-cell morphometrics highlights cell orientation, stress direction and size as the main parameters defining apical cell morphology in the dorsal pericardial wall. | Nature Communications

Fig. 1: Spatial single-cell morphometrics highlights cell orientation, stress direction and size as the main parameters defining apical cell morphology in the dorsal pericardial wall.

From: Single-cell morphometrics reveals T-box gene-dependent patterns of epithelial tension in the Second Heart field

Fig. 1: Spatial single-cell morphometrics highlights cell orientation, stress direction and size as the main parameters defining apical cell morphology in the dorsal pericardial wall.The alternative text for this image may have been generated using AI.

a Workflow for the single-cell morphometric analysis of cells in the dorsal pericardial wall. b, c Description of the cell features used for the single-cell morphometrics. d Heatmap showing the coefficients for each feature that compose each joint spatial principal component axis (jsPCA). e Heatmap showing the eigenvalues for each principal component. f Visualization of the main joint spatial PCA1 parameters: cell orientation and stress tensor in real space. g Visualization of the main jsPCA2 parameters: cell area and cell perimeter in real space. A anterior, P posterior, R right, L left, λ stress amplitude, ϑ stress main orientation, e embryo, JSPC Joint spatial principal component. N = 6 embryos, n = 8618 cells. Source data are provided as a Source Data file.

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