Fig. 6: Immune cell dynamics in developing human lung tissue.
From: High-parametric protein maps reveal the spatial organization in early-developing human lung
A Dot plots illustrating marker expression in annotated immune cell sub-clusters across each developmental week. The size of the circles indicates the percentage of cells expressing the marker in each cluster. Dark red color indicates high and white color indicates low expression. B Bar plot displaying the composition of immune cell types, with the y-axis (log scale) indicating the percentage of each immune cell type and the x-axis representing the developmental week. Cell type color assignments are displayed to the right. Source data for this figure is provided within the Source Data file. C Bar plot displaying the percentage of proliferating cells in each immune cell type for each developmental week. Cell type color assignments are displayed to the right. Source data for this figure is provided within the Source Data file. D Spatial scatterplots summarizing the spatial distribution of identified immune cell types. Cell type color assignments are consistent with those in (B) and (C). E Network models summarizing the degree of physical proximity between the immune cell stypes including their proliferating (Pro.) subsets. The line color indicates the frequency of physical proximity between the cell types, where more frequent physical proximity between two different cell types is shown in red and less frequent physical proximity is shown in yellow. The color scheme for immune cell types is consistent with those in panels (B–D), with related shades used to represent their proliferating subsets.
