Fig. 1: Phenotypic correlations between site-specific OA and any type of severe cardiovascular disease. | Nature Communications

Fig. 1: Phenotypic correlations between site-specific OA and any type of severe cardiovascular disease.

From: Shared genetic factors between osteoarthritis and cardiovascular disease may underlie common etiology

Fig. 1

Phenotypic correlations (black bars, i.e. correlations between hip osteoarthritis (OA) and knee OA, respectively, and severe cardiovascular disease in one individual) with 95% confidence interval, and parts of this correlation that are explained by additive genetic factors, common- and unique environmental factors. Analyses are performed separately by joint site, on 29 985 twin pairs, where 145 had any site OA (hip, knee and/or hand OA) and any of CVDs, 38 had hip OA and any of CVDs and 44 had knee OA and any of CVDs (pair level). Please note that the total correlation (denoted with black bars) can be lower than the sum of A and C components, when the E component has negative value. Data are presented as correlations +/− 95% confidence intervals. Source data are provided as a Source Data file.

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