Table 2 Number (percentage of all MZ/DZ twins, respectively) of pairs concordant for both osteoarthritis (OA) and cardiovascular disease (CVD)

From: Shared genetic factors between osteoarthritis and cardiovascular disease may underlie common etiology

 

Any site OA

Hip OA

Knee OA

 

MZ conc. pairs

DZ conc. pairs

MZ conc. pairs

DZ conc. pairs

MZ conc. pairs

DZ conc. pairs

Any of CVDs

64 (0.68)

81 (0.39)

18 (0.19)

20 (0.10)

22 (0.23)

22 (0.11)

Card. arr.

25 (0.26)

14 (0.07)

7 (0.07)

2 (0.01)

9 (0.09)

5 (0.02)

CHD

23 (0.24)

26 (0.13)

6 (0.06)

4 (0.02)

5 (0.05)

9 (0.04)

Heart failure

11 (0.12)

4 (0.02)

7 (0.07)

0 (0.0)

3 (0.03)

0 (0.0)

Stroke

6 (0.06)

12 (0.06)

3 (0.03)

6 (0.03)

1 (0.01)

2 (0.01)

  1. Concordance: Both twins have the OA outcome in question, and both twins have the CVD outcome in question, i.e. they are similar for the outcomes in question both within- and cross-twin. Card. arr: cardiac arrythmia, CHD coronary heart disease, MZ monozygotic, DZ dizygotic. All MZ twins: N = 9475 pairs. All DZ twins: N = 20 510 pairs.
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