Table 5 Descriptive characteristics showing degree of shared observed environmental factors, pair level

From: Shared genetic factors between osteoarthritis and cardiovascular disease may underlie common etiology

  

All MZ pairs

MZ Pairs where both twins have both OA and severe CVD

All DZ pairs

DZ Pairs where both twins have both OA and severe CVD

  

N = 9475

N = 64

N = 20 510

N = 81

Age at start of follow-up, mean (SD)

46 (17)

60 (9)

49 (16)

61 (10)

Same sex, M, n (%)

4128 (44)

34 (53)

5400 (26)

27 (33)

Same sex, F, n (%)

5347 (56)

30 (47)

6617 (32)

26 (32)

Opposite sex, n (%)

0

0

8493 (41)

28 (35)

College/university (>1 years), n (%)

  
 

Both twins high education

2258 (24)

10 (16)

3069 (15)

6 (7)

 

One twin high, one twin low education

1474 (16)

6 (9)

4835 (24)

18 (22)

 

Both twins low education

5743 (61)

48 (75)

12,606 (61)

57 (70)

Overweight, ≥25 kg/m2, n (%)

 

None of twins overweight

5799 (62)

26 (41)

9336 (46)

24 (30)

 

One twin overweight, one twin normal weight

1543 (16)

13 (20)

6376 (31)

22 (27)

 

Both twins overweight

1478 (16)

25 (39)

3040 (15)

31 (38)

Ever regular smoker, n (%)

 

None of twins smokers

2931 (31)

21 (33)

5253 (26)

20 (25)

 

One twin smoker, one twin non-smoker

1906 (20)

17 (27)

6612 (32)

37 (46)

 

Both twins smokers

4291 (45)

26 (41)

7795 (38)

24 (30)

Physical inactivity, n (%)

 

Both twins physically active

2017 (22)

13 (22)

2214 (16)

9 (17)

 

One twin physically ative, one twin physically inactive

2051 (23)

17 (28)

4005 (30)

14 (26)

 

Both twins physically inactive

3737 (42)

21 (35)

5103 (38)

19 (35)

  1. OA osteoarthritis, CVD cardiovascular disease, CHD coronary heart disease, SD standard deviation, MZ monozygotic, DZ dizygotic. *BMI data is missing for 8.05% of study population, smoking data is missing for 3.9% of study population, physical activity data is missing for 36% of the study population.