Fig. 4: KEGG ortholog (KO) enrichment is associated with sample species composition.
From: Exploring the potential of dental calculus to shed light on past human migrations in Oceania
A Heatmap of clustered samples (clusters A and B) and KOs (clusters 1, 2, and 3), showing CLR-transformed copies per million (CPM) for each ortholog. B Percent of KOs in each KO cluster from (A) in KEGG pathways present in all samples. Two-sided Wilcox test with FDR correction, ** p = 0.00272. C Mean percent contribution by genera of KOs enriched in KO Cluster 1, which are enriched in sample Cluster B. Ottowia is the most prevalent genus contributing to these KOs. D Read counts of Ottowia in all samples, aligned with panel (A), showing a higher percentage of samples in cluster B have higher Ottowia read counts than in cluster A.
