Fig. 5: Function profile of Acrasis kona developmental (Aggup) genes and their homologs in Dictyostelium discoideum AX4 (Ddi AX4).

Numbers of predicted proteins distributed among 10 general function categories are shown for A. kona Aggup accessions and their Ddi AX4 homologs. Numbers are represented by bar height for (A) A. kona Aggup accessions and their Ddi AX4 homologs expressed during active growth (0 h, RPKM > 10) and (B) A. kona Aggup accessions and their Ddi AX4 homologs after 5 h of development (mid-aggregation). Evidence supporting the functional classification of proteins and their expression levels in A. kona and Ddi AX4 are given in Supplementary Data 7. Category abbreviations are as follows: DNA replication and repair (DNA R&R), protein modification, folding, sorting and breakdown (protein fold, sort, degrade), carbohydrate chemistry (CHO chemistry), extracellular or secreted (extracell/secrete). Differential expression of Ddi AX4 genes was calculated using data from ref. ¹¹ and employing the same criteria as for A. kona (Supplementary Data 6).