Fig. 7: Prediction of Jomon ancestry and replication of phenotypic association using UKB EAS.

Jomon component prediction scores are split into deciles. The boxplot shows the distribution of observed Jomon proportions in a given decile of the predicted scores based on (a) all UKB EAS participants (n = 566), (b) EG6 (self-reported Other ethnic population; n = 200), and (c) EG5 (self-reported Chinese population; n = 308). The EG number is referred from Data-coding of UKB. d The forest plots represent the effect size of Jomon ancestry on BMI in UKB EAS, EG5, and EG6. Squares indicate the point estimates, while error bars indicate 95% confidence intervals. Asterisks represent P < 0.05 (P = 0.03 in EG6). In (a, b, c), boxes denote the interquartile range (IQR) and the median is shown as white horizontal bars; whiskers extend to 1.5 times the IQR; outliers are shown as individual points. R² indicates the squared value of the Pearson’s correlation coefficient between the prediction score and the residuals of the Jomon proportion regressed out with 10 PCs. P-values reflect two-sided tests. In (d), P-values are computed by linear regression. All statistical tests are two-sided and unadjusted for multiple comparisons.