Fig. 2: mRNA decay subgenome asymmetry.
From: Unveiling RNA structure-mediated regulations of RNA stability in wheat
a Scatter plot illustrating the variation in decay rates between the A and B subgenomes in Kronos. The decay rates of A subgenome genes show either significantly higher or lower values compared to those in the B subgenome, or exhibit no significant difference between the two subgenomes. (A < B, npairs = 3414; A > B, npairs = 3184; NSD, no significant difference, npairs = 6350, by one-sided student’s t-test, FC, fold change). b, c Representative examples illustrating mRNA decay subgenome asymmetry. The bar plot represents the steady-state relative mRNA abundance (***p < 0.001 by one-sided student’s t-test). The line plot depicts the degradation trend of the gene pairs (error bars indicating ± SEM, nreplicate samples = 3; b p = 6.55e-08, c p = 1.76e-08, one-sided repeated measures ANOVA test). d, e The correlations between the differential mRNA decay rates and the differential steady-state mRNA abundances for homoeologous gene pairs. (r = 0.33 and 0.27, p < 2.2e-16, two-sided Pearson correlation test). f Gene ontology (GO) analysis. The half-life of each point corresponds to the average of the half-lives of homoeologous gene sets in subgenome A and B within the corresponding enriched GO categories. The size of the points represents the degree of enrichment for the corresponding GO term. The colors in the GO functional heatmap are determined by the fold change values of the Adecay rate/Bdecay rate.
