Fig. 5: STING@nanomotor to inhibit bladder cancer growth by inducing antitumor immunity.

a Diagram depicting the generation of MB49 bladder cancer in B6 mice and the treatment schedule. b Representative images for the comparison of tumor growth by H&E staining of bladder cancers (upper panel) and the CD8 T cell infiltration (lower panel) after each treatment. The H&E staining images are representative of 6 independent experiments and CD8 T cell immunohistochemical images are representative of 5 independent experiments. c Quantitative analysis for the tumor thickness and the CD8 T cell infiltration. Data are presented as mean values and error bars represent the S.D. and statistical analysis was performed via two-sided t-test (n = 6 mice per group). d Diagram depicting the generation of MB49 bladder cancer and the treatment schedule to measure mRNA expression in the bladder. e mRNA expression of indicated genes following each treatment. Data are presented as mean values and error bars represent the S.D., and statistical analysis was performed via two-sided t-test (n = 5 mice per group). Source data are provided as a Source Data file.