Fig. 1: Design of organocatalytic enantioselective synthesis of inherently chiral sulfur-containing calix[4]arenes.
![Fig. 1: Design of organocatalytic enantioselective synthesis of inherently chiral sulfur-containing calix[4]arenes.](http://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-024-54380-1/MediaObjects/41467_2024_54380_Fig1_HTML.png)
a State of the art of asymmetric electrophilic sulfenylation of arenes. b Previous work on catalytic asymmetric synthesis of inherently chiral calix[4]arenes. c Our design for organocatalytic enantioselective synthesis of inherently chiral calix[4]arenes via an intermolecular electrophilic sulfenylation reaction. d Chiral sulfide catalyzed sulfenylation of calix[4]arenes. HFIP hexafluoroisopropanol.