Fig. 6: RNAseq analysis of GZNL-P36 in SARS-CoV-2 infected Mice. | Nature Communications

Fig. 6: RNAseq analysis of GZNL-P36 in SARS-CoV-2 infected Mice.

From: Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19

Fig. 6: RNAseq analysis of GZNL-P36 in SARS-CoV-2 infected Mice.

GSVA scores of selected genesets on bulk RNAseq data of GZNL-P36 in SARS-CoV-2 infected Mice (n = 5 per group). Genesets were obtained from MSigDB and curated based on a criterion of including keywords such as “SARS” or “COVID”. The data were then scaled, GSVA scores ranging from -1 (blue, down-regulated) to 1 (red, up-regulated). Source data are provided as a Source Data file.

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