Fig. 1: Schematic illustrations of nuclear pore complexes (NPCs) and their mimicries of solid or liquid natures.
From: Coacervate-pore complexes for selective molecular transport and dynamic reconfiguration
a The molecular machinery of an NPC featuring a central channel filled with FG-rich proteins to act as a molecular sieve. b Two solid constructs based on surface-grafted brushes and crosslinked polymers, where the spatial fixations are highlighted by purple staples. c A liquid construct based on coacervate-pore complexes (CPCs). d The liquid coacervates are made of small molecules (red and blue), polyelectrolytes (orange and green), or proteins (yellow and purple). e Inhabitation of coacervate droplets into a pore of diameter (Φ) is a spontaneous process as driven by the capillary pressure (Pc), given that the contact angle (θ) is smaller than 90 °. The Laplace pressure (PL) has a minor effect. f Four features of some CPCs.
