Fig. 5: Biofilm subpopulations are characterized by diverse gene expression profiles. | Nature Communications

Fig. 5: Biofilm subpopulations are characterized by diverse gene expression profiles.

From: Bacterial single-cell RNA sequencing captures biofilm transcriptional heterogeneity and differential responses to immune pressure

Fig. 5

A Dot plot with top marker genes per cluster from the biofilm control sample. All marker genes have FDR-adjusted p-value ≤ 0.05. The UMAP plot is shown above for reference as defined in Fig. 4B, and clusters are arranged in the plot according to transcriptional relationship, as illustrated in the dendrogram. A more detailed list of genes can be found in Table 1. ECFTS energy coupling factor transporter S, MFS major facilitator superfamily. Source data are provided as a Source Data file. B–D Marker gene expression overlaid on the UMAP plot for cluster 1 – n = 999 cells (B), cluster 5 – n = 272 cells (C), and cluster 3 – n = 288 cells (D). Color represents normalized expression per cell.

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