Table 3 Summary of clinical responses to adoptive T cell therapy
From: Compassionate access to virus-specific T cells for adoptive immunotherapy over 15 years
Total | Virological/Disease Response | Remained Virus/ Disease Free | No Response | Unknown | |
|---|---|---|---|---|---|
HSCT | |||||
Paediatric | |||||
Adenovirus | 6 | 5 | - | 1 | - |
Cytomegalovirus | 9 | 6 | 1 | 2 | - |
Epstein–Barr virus | 2 | 2 | - | - | - |
Polyomavirus (BKV/JCV) | 3 | 1 | - | 2 | - |
Multiple Viruses | 3 | 2 | 1 | - | - |
Adult | |||||
Cytomegalovirus | 14 | 6 | 2 | 6 | - |
Epstein–Barr virus | 4 | - | 1 | 3 | - |
Polyomavirus (BKV/JCV) | 4 | 4 | - | - | - |
Multiple Viruses | 5 | 4 | - | 1 | - |
SOT | |||||
Paediatric | |||||
Cytomegalovirus | 1 | 1 | - | - | - |
Epstein–Barr virus | 4 | 3 | 1 | - | - |
Adult | |||||
Cytomegalovirus | 5 | 4 | - | - | 1 |
Epstein–Barr virus | 3 | 2 | - | 1 | - |
Polyomavirus (BKV/JCV) | 4 | 3 | - | 1 | - |
No Transplant | |||||
Paediatric | |||||
Adenovirus | 1 | - | - | 1 | - |
Epstein–Barr virus | 2 | - | 1 | 1 | - |
Adult | |||||
Cytomegalovirus | 2 | - | - | 2 | - |
Epstein–Barr virus | 3 | 1 | - | 2 | - |
Polyomavirus (BKV/JCV) | 3 | 2 | - | 1 | - |
Total | 78 | 46 | 7* | 24 | 1 |
