Fig. 4: Enantioselective unsymmetrical 1,2-diamination of azlactones via the (3 + 2) reaction.
From: Azocarboxamide-enabled enantioselective regiodivergent unsymmetrical 1,2-diaminations
Reaction conditions: 1 (0.15 mmol), 4 (0.15 mmol), and CPA-3 (5 mol%) in toluene (1 mL) at r.t. for 5 h, isolated yields, ee values were determined by chiral stationary HPLC.
