Fig. 2: Higher levels of soluble and cellular markers of inflammation and immune activation in ART-treated people with HIV. | Nature Communications

Fig. 2: Higher levels of soluble and cellular markers of inflammation and immune activation in ART-treated people with HIV.

From: Chronic inflammation degrades CD4 T cell immunity to prior vaccines in treated HIV infection

Fig. 2: Higher levels of soluble and cellular markers of inflammation and immune activation in ART-treated people with HIV.The alternative text for this image may have been generated using AI.

A Plasma levels of CRP, CXCL13, IFNγ, IL-4, IL-6, IL-8, IL10, IL12, MIP1β and TNF. B Plasma levels of sCD14, sCD163, IFABP and LBP. C Blood frequencies of HLA-DR+, PD-1+ and CD57+ CD4 or CD8 T cells as well as frequencies of CD56high NK cells and monocytes. Circles represent individual participants (33 HU; 34 HIV), medians and IQR are shown, comparison between groups was performed by two-tailed Mann–Whitney tests and P-values of comparisons are presented. D Fold differences of univariate comparisons for plasma markers and cell frequencies between HIV-CMV seropositive and HU-CMV seropositive participants as determined by two-tailed Mann–Whitney tests without adjustment for multiple comparison. Source data are provided as a Source Data file.

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