Fig. 7: Integrative analysis of plasma, cell markers, cell subsets and transcriptome of MV or TT-stimulated CD4 T cell subsets.

A Arc diagram of correlations between plasma cytokines, T cell markers and subsets enriched in the HIV-infected group, recall responses and Hallmark pathways across HIV-infected and uninfected groups. Color of the edges between nodes indicates Spearman correlations. Color intensity and the size of the edges are proportional to the correlation coefficients. B Percentages of CD69⁺, IFNγ⁺ and difference in percentages of PD1⁺ memory CD4 T cells of 15 ART-treated HIV people upon stimulation with rosuvastatin (ROS), tocilizumab (TCZ) or SEB compared to the unstimulated condition. C Difference in percentages of CD69⁺, IFNγ⁺ and PD1⁺ memory CD4 T cells of 15 ART-treated HIV people upon stimulation with SEB+ROS or SEB+TCZ compared to SEB alone. Medians and interquartile range are shown, and comparisons between unstimulated, SEB, ROS or TCZ conditions were performed by two-tailed Wilcoxon paired test. Source data are provided as a Source Data file.