Table 1 Top MSigDB VAX gene sets up- or downregulated in HIV-infected compared to uninfected
From: Chronic inflammation degrades CD4 T cell immunity to prior vaccines in treated HIV infection
MSigDB VAX gene sets | P-adj | NES | Size | LE | |
|---|---|---|---|---|---|
Unstimulated CD154neg HIV-infected vs uninfected | |||||
Up in HIV | KAZMIN_PBMC_P_FAL._RTSS_AS01_AGE_UNKNOWN_CORR._WITH_PROTECTION_56DY_NEG. | 1.9E-05 | 0.68 | 2.13 | 41 |
Down in HIV | None | ||||
MV CD154neg HIV-infected vs uninfected | |||||
Up in HIV | HOFT_PBMC_TICE_BCG_RBCG_AG85A_AG85B_AGE_18_40YO_CORR._W_W_BL._BAC._ACT._NEG. | 9.0E-05 | 0.62 | 1.97 | 40 |
Down in HIV | HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_UP | 5.3E-11 | −0.45 | −1.63 | 752 |
MV CD154pos HIV-infected vs uninfected | |||||
Up in HIV | FLETCHER_PBMC_BCG_10W_INFANT_PPD_STIMULATED_VS_UNSTIMULATED_10W_UP | 1.6E-08 | 0.67 | 2.14 | 83 |
Down in HIV | HOWARD_T_CELL_INACT_MONOV_INFL._A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP | 1.1E-07 | −0.75 | −2.31 | 42 |
TT CD154neg HIV-infected vs uninfected | |||||
Up in HIV | KAZMIN_PBMC_P_FAL._RTSS_AS01_AGE_UNKNOWN_CORR._WITH_PROTECTION_56DY_NEG. | 3.5E-4 | 0.63 | 1.89 | 41 |
Down in HIV | HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_UP | 5.3E-13 | −0.42 | −1.77 | 752 |
TT CD154pos HIV-infected vs uninfected | |||||
Up in HIV | FLETCHER_PBMC_BCG_10W_INFANT_PPD_STIMULATED_VS_UNSTIMULATED_10W_UP | 5.7E-10 | 0.63 | 2.47 | 83 |
Down in HIV | HOWARD_DENDR._CELL_INACT_MONOV_INFL._A_IND._05_2005_H5N1_AGE_18_49YO_1DY_UP | 7.1E-07 | −0.60 | −1.73 | 141 |
