Fig. 3: Structural clustering identifies differently grouped protein groups. | Nature Communications

Fig. 3: Structural clustering identifies differently grouped protein groups.

From: A proteome-wide structural systems approach reveals insights into protein families of all human herpesviruses

Fig. 3

A Structural alignment of the HCMV UL112-113 cluster. Only the conserved beta-barrel-like domain is shown for clarity of HCMV UL112-113, HHV-6A U79_U80, HHV-6B U79, HHV-7 U79, HSV-1 UL4, HSV-2 UL4, and VZV ORF56. B Structural alignment of the LANA DNA binding domain-containing cluster with only the matching domain shown for clarity of KSHV ORF73, EBV EBNA1, HHV-6A U84, HCMV UL117, HCMV UL122, HCMV UL123, HHV-6A U86, HHV-6A U90_U87U86, HHV-6B U84, HHV-6B U90_U86, HHV-7 U84, HHV-7 U86, HSV-1 UL3, HSV-2 UL3, and VZV ORF58. C Ig-like domain-containing cluster harboring the HCMV RL11 protein family. The canonical members are marked with a black outline. D Structural alignment of HCMV RL11 with HCMV RL13. The blue arrow points to the additional beta strand. The corresponding UCSF ChimeraX sessions can be found at https://zenodo.org/records/13284140.

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