Fig. 4: Fine-mapped TR associations underlying quantitative traits in the UKB.
A A CGC repeat within the 5′UTR of GNB2 associated with pulse rate. B A 20mer repeat within the 5′UTR of EIF4A3 associates with reticulocyte percentage. C An AC repeat within the 3’UTR of WNT9A associates with standing height. Bar charts above each plot indicate the relative frequency of averaged TR allele sizes in the UKB cohort. The regression slope is shown as a solid blue line and we show the trait distributions per allele size. Within each violin, red circles show the medians; box limits indicate the 25th and 75th percentiles; whiskers extend 1.5 times the interquartile range from the 25th and 75th percentiles. P values shown were calculated using linear regression implemented in REGENIE. Each plot shows data from a total of between 160,365 and 168,173 individuals, with a minimum of 167 individuals plotted per violin.
