Fig. 4: Discrimination of virus culture positivity by blood transcript levels of MX1 and IFI27. | Nature Communications

Fig. 4: Discrimination of virus culture positivity by blood transcript levels of MX1 and IFI27.

From: SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections

Fig. 4: Discrimination of virus culture positivity by blood transcript levels of MX1 and IFI27.

A Individual standardised blood transcript levels of MX1 and IFI27 at each time point for all individuals who develop replicative infection (N = 17), stratified by contemporary virus culture positivity in either nose or throat swabs, with dashed line to represent the threshold (Z > 2) for elevated transcript levels. B Area under the receiver operating characteristic curve (AUROC) discrimination of virus culture positivity by blood transcript levels of MX1 and IFI27 across all time points, showing AUROC point estimates and 95% confidence intervals.

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