Table 3 Intact and defective proviral DNA in tissues at necropsy

From: SHIV remission in macaques with early treatment initiation and ultra long-lasting antiviral activity

  

Provirus (copies/106 cells)

 

Macaque ID

Intact

3’ defective

5’ defective

Total

eART

 Mesenteric LN

10–47

59

<48*

<48

59

27300

<81

<81

<81

<81

28025

3

<2

<2

3

30622

<5

<5

<5

<5

 Inguinal LN

10–47

<35

<35

<35

<35

27300

<2

<2

2

2

 Axillary LN

10–47

<8

8

<8

8

28025

<9

<9

<9

<9

 Spleen

28025

<63

<63

65

65

30622

<3

<3

6

6

eART + VES

 Mesenteric LN

MAJ

<4.87

<4.87

<4.87

<4.87

44174

<2.74

<2.74

6

6

44346

1401

163

527

2090

Untreated controls

 Mesenteric LN

09–19

26,068

58

1062

27,183

10–87

2780

338

607

3725

  1. *the frequency of undetectable was calculated based on assay cell input.
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