Fig. 4: WMH-SynthSeg can automatically segment WMH on LF-MRI FLAIR sequences in patients presenting without neurologic complaints yet concomitant vascular risk factors.
From: Portable, low-field magnetic resonance imaging for evaluation of Alzheimer’s disease
a An example of a subject with WMH at HF- and LF-MRI, with automatically segmented lesions outlined (blue) in the axial plane and with 3D rendering. b) WMH volume scatterplot and linear fit of WMH volumes derived at LF- compared to HF-MRI using WMH-SynthSeg (r = 0.91, p < 0.001). c Scatterplot of WMH volumes derived from automatic segmentation versus manual outlining at HF, and similarly at LF in (d). WMH volume (n = 23) was associated with the periventricular Fazekas score (e), the deep Fazekas score in (f), and the composite Fazekas score in (g). For each subpanel, the box plots shows the median, the interquartile range, and the Tukey whiskers. Source data is available via the following link: https://doi.org/10.7910/DVN/9PANMC. WMH, white matter hyperintensity volume; LF, low-field; HF, high-field.
